文献支持APPL1 Polyclonal Antibody_货号:E-AB-10172_多克隆抗体

Verified Samples in WB:A172
Verified Samples in IHC:Human esophagus cancer,Human lung cancer

WB 1:500-1:2000, IHC 1:100-1:300

Polyclonal

IgG

Recombinant protein of human APPL1

APPL1

Adapter protein containing PH domain;Adaptor Protein Containing pH Domain;Adaptor protein containing pH domain PTB domain and leucine zipper motif 1;Adaptor protein containing pH domain PTB domain and leucine zipper motif;Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1;AKT2 INTERACTOR;APPL 1;Appl1;DCC interacting protein 13 alpha;DCC-interacting protein 13-alpha;DIP 13 alpha;DIP13 alpha;Dip13-alpha;DIP13alpha;DP13A;KIAA1428;PTB domain and leucine zipper motif 1;PTB Domain and Leucine Zipper Motif;Signaling adaptor protein DIP13alpha抗体

Q9UKG1

80kDa

Early endosome membrane. Nucleus. Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.

0.1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cell Biology; Developmental Biology; Neuroscience; Signal Transduction

Unconjugated

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.