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库存 :现货
英文名 :FectoVIR®-AAV
CAS号 :/
保质期 :/
供应商 :纽祺(上海)健康科技有限公司
保存条件 :5±3℃
规格 :1ml
- Superior Performance: highest AAV titers for increased number of doses per batch 卓越的性能:最高的AAV滴度增加剂量的批次
- Scalable: robust and flexible to support small to large scale production 可扩展:健壮和灵活,支持小到大规模的生产
- Cost-effective: reduced cost per dose for therapy affordability 成本效益:降低每剂治疗的成本
- Accelerated time to market: performance and scalability for faster process development 加速上市时间:更快流程开发的性能和可伸缩性
- Trustworthy: #1 transfection supplier of Gene & Cell therapy 值得信赖:基因和细胞治疗的头号转染供应商
Overview(概述)
Specifications(规范)
Reagent
试剂FectoVIR®-AAV
Molecule delivered
转染核酸Plasmid DNA and co-delivery of several plasmid DNA
质粒DNA,多质粒DNA的共转Applications
应用Recombinant AAV virus production in suspension cells
在悬浮细胞中生产重组 AAV 病毒Virus types
病毒类型Adeno-Associated Viruses (AAV)
腺相关病毒 (AAV)Cell types
细胞类型Mammalian producer cell lines (HEK-293, HEK-293 derivatives) grown in suspension cultures
悬浮培养的哺乳动物细胞系(HEK-293, HEK-293系)Number of transfections
试剂用量100 mL of FectoVIR®-AAV transfection reagent is sufficient to transfect on average 50 L of cell culture
100 mL的FectoVIR®-AAV 至少转染50 L培养液Storage
储存条件5 ± 3 °C, stable for at least 9 months when stored appropriately
5 ± 3 °C, 至少18 个月Provided with
配套提供Protocol
Certificate of Analysis
Certificate of Origin
Non-Hazardous Product Statement
操作说明书
COA分析报告
无动物来源声明
无危害声明
Summary(总结)AAVs are becoming the leading viral vector in the development of gene-based advanced therapy medicinal products (ATMPs). Their success is due to their intrinsic properties: they are primarily non-integrating as they persist within cells as episomes, and have a broad tropism with eleven serotypes that have the ability to infect specific cell types. A major challenge today is manufacturing sufficient quantities of AAV in order to treat larger groups of patients. FectoVIR®-AAV is a novel class of animal free transfection reagent specifically developed for industrial scale production of recombinant AAV (rAAV) viral vectors in suspension HEK-293 cell types. FectoVIR®-AAV transfection reagent guarantees higher rAAV viral titers, improved flexibility and scalability for industrial scale manufacturing.
aav正在成为基于基因的先进治疗药物(ATMPs)开发的主要病毒载体。它们的成功是由于它们的内在特性:它们主要是不整合的,因为它们以集集体的形式存在于细胞内,并具有广泛的趋同性,具有感染特定细胞类型的能力的11种血清型。今天的一个主要挑战是生产足够数量的AAV,以治疗更大的患者群体。FectoVIR®-AAV是一种新型的动物无转染试剂,专门开发用于工业规模生产重组AAV (rAAV)病毒载体悬浮HEK-293细胞类型。FectoVIR®-AAV转染试剂保证了更高的rAAV病毒滴度,提高了工业规模生产的灵活性和可扩展性。A Frequently Asked Question section about FectoVIR®-AAV can be found here.
关于FectoVIR®-AAV的常见问题可以在这里找到。
Read FAQ(阅读常见问题)Ordering information(订购信息)
Reference Number Amount of reagent 101000044 FectoVIR®-AAV 1 mL
纽祺(上海)健康科技有限公司
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入驻年限:4年