[CAS 29261-12-9] | 25,26-Dihydroxyvitamin D3 | ChemeGen

保存条件 ：4℃/-20℃

保质期 ：2年

英文名 ：25,26-Dihydroxyvitamin D3

库存 ：大量

供应商 ：ChemeGen

CAS号 ：29261-12-9

规格 ：1 mg

官网网址：www.chemegen.com
25,26-Dihydroxyvitamin D3(25,26-dihydroxycholecalciferol) is a metabolite of vitamin D3 with intestinal calcium transport activity.IC50 value:Target: VD metaboliteThe biological activity of synthetic 24,25 and 25,26 diOHD3 was studied in vitamin D-deficient rats. The purpose of this study was to investigate the influence of small doses of both metabolites (0.125-0.250 mug) upon intestinal calcium transport and bone calcium mobilization. Both metabolites were able to increase calcium absorption in rats maintained on a calcium-deficient diet, but failed to do it in rats on a normal calcium diet. Bilateral nephrectomy suppressed this effect. The "bone calcium mobilization" of both derivatives was measured in vitamin D and calcium- or phosphorus-deprived rats after one intravenous dose. When serum calcium was initially low, 24,25 and 25,26 diOHD3 increased serum calcium moderately, but the increment was only significant with 24,25 diOHD3. ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商，致力于为广大科研、商业实验室的科学研究者提供高品质的产品与技术服务，不断促进生命科学领域的新技术发展。