Cathepsin L Inhibitor

保存条件 ：-20

保质期 ：Cathepsin L inhibitor is a potent inhibitor of cathepsin L (IC50 = 0.85 nM).{41143} It is selective for cathepsin L over calpain II and cathepsin B (IC50s = 184, and 85.1 nM, respectively). It is trypanocidal with an ED50 value of 45 nM against T. bruce

英文名 ：SB 412515

库存 ：1 mg, 10 mg, 25 mg, 5 mg

供应商 ：Cayman

CAS号 ：167498-29-5

规格 ：This biochemical is available in the following size(s) 25 mg, 5 mg, 50 mg - Please inquire

A potent cathepsin L inhibitor (IC50 = 0.85 nM); selective for cathepsin L over calpain II and cathepsin B (IC50s = 184, and 85.1 nM, respectively); trypanocidal against T. brucei (ED50 = 45 nM); completely suppresses osteoclastic pit formation on femur slices isolated from bovine cortical bone at a concentration of 1 μg/ml; inhibits bone loss in a mouse model of osteoporosis in a dose-dependent manner