Ro 106-9920

保存条件 ：-20

保质期 ：Transcriptional activation by NF-κB is limited by IκBα binding, which masks the NF-κB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IκBα for degradation, enabling NF-κB to p

库存 ：1 mg, 10 mg, 5 mg

供应商 ：Cayman

CAS号 ：62645-28-7

A small molecule inhibitor of NF-κB-dependent expression of TNF-α, IL-1β, and IL-6 (IC50 50 = 2.3 µM)