N-Acetyl Puromycin n -乙酰嘌呤霉素 22852-13-7

保存条件 ：零下20度

保质期 ：3年

英文名 ：N-Acetyl Puromycin

库存 ：大量

供应商 ：上海惠诚生物科技有限公司

CAS号 ：22852-13-7

规格 ：5 mg/25 mg

N-Acetyl Puromycin (22852-13-7) down regulates SnoN and Ski protein expression. Induces TGF-β signaling, independently of MAPK activation. Does not bind ribosomes or block protein synthesis.
n -乙酰嘌呤霉素(22852-13-7)下调SnoN和Ski蛋白的表达。 诱导TGF-β信号转导，独立于MAPK激活。 不结合核糖体或阻止蛋白质合成。

References/Citations:

1) Hernandez-Damian et al. (2013), Downregulation of SnoN oncoprotein induced by antibiotics anisomycin and puromycin positively regulates transforming growth factor-β signals; Biochim. Biophys. Acta, 1830 5049

CAS:
22852-13-7
Catalog Number:
10-1591
Activity:
Down regulates SnoN and Ski expression
Chemical Name:
3’-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3’-deoxy-N,N-dimethyladenosine
Molecular Weight:
513.55
Molecular Formula:
C₂₄H₃₁N₇O₆
Solubility:
Soluble in DMSO (up to 70 mg/ml) or in DMF (up to 55 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.
Shipping Code:
RT